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A structural snapshot of a phosphohistidine analogue (ball and stick model) nestled at the interface between different areas (green, brown) of a phosphohistidine antibody. Such structures provide insights into the molecular properties of the antibodies, which makes them useful for revealing elusive phosphohistidine-containing proteins in cells. Credit: Salk Institute
Xray crystallography and recombinant antibodies uncover workings of an elusive molecule central to human health. In structural biology, some molecules are so unusual they can only be captured with a unique set of tools...
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