Previous research looked at high doses of purified resveratrol to study its potential to prevent cancer. This is the first study to look at the effects of a lower daily dose – equivalent to the amount of resveratrol found in one large (approx. 250ml) glass of red wine vs dose 200X higher. Results from bowel cancer-prone mice given the smaller dose showed a 50% reduction in tumour size while the high dose showed a 25% reduction. Lower doses of resveratrol were twice as effective as the higher dose in stopping tumours growing, although this effect was only seen in animals fed a high-fat diet.
Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth...
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