Regulatory DC immunotherapy can be effective for food allergies and suggest that induction of Foxp3− regulatory T cells might be a useful strategy for tolerance induction in this context.
A new immunotherapy technique has been developed that nearly eliminates the allergic response to peanut and egg white proteins in food-allergic mice, reducing the anaphylactic response by up to 90% with only one treatment. The findings open the door to test this new allergy treatment in “humanized mice” – mice with non-existent immune systems implanted with cells from a human immune system, eg, from a peanut-allergic person. With Health Canada approval, the first human trial could begin in about one year, Gordon said.
“If we can reliably ‘cure’ food allergies, or related conditions such as asthma or aut...
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