Regenerative Bandage tagged posts

The regenerative bandage promotes cell spreading and proliferation. The green spots are live cells entrapped in the hydrogel and stained with Calcein-AM. Credit: Ameer Research Lab, Northwestern University

Shape-conforming hydrogel leverages the body’s own healing mechanisms rather than releasing drugs or biologics. Researchers have developed a new device, called a regenerative bandage, that quickly heals painful, hard-to-treat sores without using drugs. During head-to-head tests, the new bandage healed diabetic wounds 33% faster than one of the most popular bandages currently on the market.

“The novelty is that we identified a segment of a protein in skin that is important to wound healing, made the segment and incorporated it into an antioxidant molecule that self-aggregates at body temp...

Sustained release of stromal cell derived factor-1 from an antioxidant thermoresponsive hydrogel enhances dermal wound healing in diabetes

Antioxidant bandage delivers healing protein. At some point in their lives, 15% of people with diabetes will develop a painful and hard-to-treat foot ulcer. 24% percent of those affected will require a lower-leg amputation because of it. And, in some instances, what seems like a harmless sore might even lead to death. A Northwestern University team has developed a new treatment. Called a “regenerative bandage,” the novel material heals diabetic wounds 4X faster than a standard bandage and has the added benefit of promoting healing without side effects.

“Foot ulcers cause many serious problems for diabetic patients,” said Prof. Guillermo Ameer...