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    Potential Relief for Osteoarthritis moves to Clinical Trial after Animal Studies

    March 28, 2023, Categories  Biology/Biotechnology, Health/Medical

    The image on the left shows damaged osteoarthritic cartilage without treatment in animal studies, and the image on the right shows regeneration of articular cartilage after knee injection of the new drug R805/CX-011. (Image: Evseenko Lab/USC Stem Cell)
    The image on the left shows damaged osteoarthritic cartilage without treatment in animal studies, and the image on the right shows regeneration of articular cartilage after knee injection of the new drug R805/CX-011. (Image: Evseenko Lab/USC Stem Cell)

    A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

    The findings, published March 22nd in Science Translational Medicine, indicate that a drug compound, R805/CX-011, may modulate an important cell receptor in the body’s immune system, GP130, that signals when antibodies should attack a virus or infection...

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