Left: Magnetic resonance imaging (MRI) of the heart of a patient after a heart attack. Right: key. 1: left ventricle, 2: left atrium, 3: right ventricle. The major heart muscle surrounds the left ventricle, and healthy muscle appears black on MRI. After an infarction, the necrotic portion of the heart appears white on MRI after injectino of a contrast agent. Credit: CNIC
Scientists at CNIC have discovered a new mechanism of action of metoprolol, a drug that can reduce the damage produced during a heart attack if administered early. Rapid administration of metoprolol during a heart attack directly inhibits the inflammatory action of neutrophils. The reduced inflammation translates into a smaller area of damaged tissue in the post-infarcted heart...
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