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    reprogramming cells for heart repair tagged posts

    Reprogramming Cells for Heart Repair: New Method Transforms Ordinary Fibroblasts into Mature Cardiomyocytes

    December 26, 2024, Categories  Biology/Biotechnology, Health/Medical

    Researchers from Korea University explore how ascorbic acid and FGF4 revolutionize regenerative medicine
    This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This approach effectively reprograms fibroblasts into cardiomyocytes with improved structure and function, offering exciting possibilities for regenerative medicine. Credit: The author

    Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year. Damage caused by these diseases is particularly difficult to repair, since the heart has minimal ability to regenerate itself. But what if we could reprogram the body’s own cells to restore damaged tissue?

    This question has been tackled by scientists at Korea University, led by Dr...

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