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    3D-printed Biomaterials that Degrade on Demand

    September 9, 2017, Categories  Biology/Biotechnology, Health/Medical

    Brown researchers have found a way to 3-D print intricate temporary microstructures that can be degraded on demand using a biocompatible chemical trigger. The technique could be useful could be useful in fabricating microfluidic devices, creating biomaterials that respond dynamically to stimuli and in patterning artificial tissue. Credit: Wong Lab / Brown University

    Stereolithographic Printing of Ionically-Crosslinked Alginate Hydrogels for Degradable Biomaterials and Microfluidics. Lab Chip, 2017; DOI: 10.1039/C7LC00694B

    Brown University engineers have demonstrated a technique for making 3D-printed biomaterials that can degrade on demand, which can be useful in making intricately patterned microfluidic devices or in making cell cultures than can change dynamically during experiments. “It’s a bit like Legos,” said Ian Wong, an assistant professor in Brown’s School of Engineering and co-author of the research. “We can attach polymers together to build 3D structures, and then gently detach them again under biocompatible conditions.”

    They made their new degradable structures using a type of 3D printing called stereolithography...

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