Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.
The technique, known as RIFLE – rotational internal flow layer engineering – enables the construction of separate layers as delicate as one cell thick.
Such versatility is crucial to developing accurate human models of layered tubular tissue for use in research, offering an important alternative to animal models, experts say.
Scientists have been able to demonstrate the technology by manufacturing cells into super-thin layers that mirror those seen in a human blood vessel.
Layered tubular tissue is found throughout the body — in blood vessels, the digestive tract and other organs...
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