Harmful intestinal inflammation might be prevented with a one-two punch. Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
The potential treatment pathway emerges from a study led by experts at Cincinnati Children’s published online March 28, 2023, in the Journal of Experimental Medicine. Co-first authors were Garrett Overcast, PhD, and Hannah Meibers, BS. Corresponding author was Chandrashekhar Pasare, DVM, PhD, Division of Immunobiology and co-director, Center for Inflammation and Tolerance.
The research team conducted numerous experiments to learn about how immune cells located in the lining of the intestin...
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