sarcopenia tagged posts

New University of East Anglia (UEA) research shows that vitamin C could help over 50s retain muscle mass in later life. The study shows that older people who eat plenty of vitamin C – commonly found in citrus fruits, berries and vegetables – have the best skeletal muscle mass.

This is important because people tend to lose skeletal muscle mass as they get older — leading to sarcopenia (a condition characterised by loss of skeletal muscle mass and function), frailty and reduced quality of life.

Lead researcher Prof Ailsa Welch, from UEA’s Norwich Medical School said: “As people age, they lose skeletal muscle mass and strength.

“People over 50 lose up to one per cent of their skeletal muscle mass each year, and this loss is thought to affect more than 50 million people worldwide.”

“It’s a...

Proposed mechanism of skeletal muscle mitochondria involvement in sarcopenia

Muscle wastage and loss of strength, ie sarcopenia causes loss of quality of life. At about 55 years old, people begin to lose muscle mass, this loss continues into old age, at which point it becomes critical. The underlying causes of sarcopenia are unknown and thus no treatment is available for this condition. A study has discovered that Mitofusin 2 is required to preserve healthy muscles in mice. This protein could serve as a therapeutic target to ameliorate sarcopenia in the elderly.

They demonstrate that low activity of this protein in 24-month old mice (equivalent of a person aged 80) is directly associated with muscle wastage and sarcopenia observed...