SARS-CoV-2 tagged posts

Compound in the Herb Rosemary may be useful against COVID-19 and other Inflammatory Diseases

The chemical structures of the ingredients of Rosemary extract.

A team co-led by scientists at Scripps Research has found evidence that a compound contained in the medicinal and culinary herb rosemary could be a two-pronged weapon against the SARS-CoV-2 coronavirus that causes COVID-19.

The scientists, in experiments described in a paper published January 6, 2022 in the journal Antioxidants, found that the compound, carnosic acid, can block the interaction between the SARS-CoV-2 outer “spike” protein and the receptor protein, ACE2, which the virus uses to gain entry to cells.

The team also presented evidence, and reviewed evidence from prior studies, that carnosic acid has a separate effect in inhibiting a powerful inflammatory pathway—a pathway that is active in severe COVID-19 ...

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How many people get ‘Long COVID’? More than Half, researchers find

More than half of the millions of people who have been diagnosed with COVID-19 worldwide since December 2019 will experience post-COVID symptoms up to six months after recovering, according to a study by Penn State College of Medicine researchers. 
 IMAGE: GETTY IMAGES | ECLIPSE_IMAGES

Half of COVID survivors experience lingering symptoms six months after recovery. More than half of the 236 million people who have been diagnosed with COVID-19 worldwide since December 2019 will experience post-COVID symptoms — more commonly known as “long COVID” — up to six months after recovering, according to Penn State College of Medicine researchers...

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Study links Severe COVID-19 to Increase in Self-Attacking Antibodies

An illustration of antibodies among blood cells.
SciePro/Shutterstock.com

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies than people without COVID-19, according to a new study. Autoantibodies can be early harbingers of full-blown autoimmune disease. “If you get sick enough from COVID-19 to end up in the hospital, you may not be out of the woods even after you recover,” said PJ Utz, MD, professor of immunology and rheumatology at Stanford Medicine.

Utz shares senior authorship of the study, which will be published Sept...

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3D ‘Assembloid’ shows how SARS-CoV-2 infects Brain Cells

Figure depicts SARS-CoV-2 spreading through blood vessels (green) to infect pericytes (red), which amplify infection and can spread infection to other cell types in the brain.
CREDIT
UC San Diego Health Sciences

Researchers at University of California San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

The findings are published in the July 9, 2021 online issue of Nature Medicine.

“Clinical and epidemiological observations suggest that the brain can become involved in SARS-CoV-2 infection,” said senior author Joseph Gleeson, MD, Rady Professor of Neuroscience at UC San Diego School of Medicine and director of n...

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