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    Self-assembling Nanofibers tagged posts

    Self-assembling Nanofibers Prevent Damage from Inflammation

    April 17, 2021, Categories  Biology/Biotechnology, Health/Medical

    The graphic shows the peptide nanofiber bearing complement protein C3dg (blue) and key components of the TNF protein, which include B-cell epitopes (green), and T-cell epitopes (purple). Credit: Chelsea Fries
    The graphic shows the peptide nanofiber bearing complement protein C3dg (blue) and key components of the TNF protein, which include B-cell epitopes (green), and T-cell epitopes (purple). Credit: Chelsea Fries

    Nanomaterials strategically activate the immune system to fight inflammation as effectively as current standard therapeutics

    Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system. In mouse models of psoriasis, the nanofiber-based drug has been shown to mitigate damaging inflammation as effectively as a gold-standard therapy.

    One of the hallmarks of inflammatory diseases, like rheumatoid arthritis, Crohn’s disease and psoriasis, is the overpr...

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