serine palmitoyltransferase tagged posts

Skin’s Protective Chains uncovered

Structures and nomenclature of human ceramide classes. A and B: Structures of LCBs (A) and FAs (B) in human ceramides. The abbreviations used in this study are shown in parentheses after each compound name, and those recommended by LIPID MAPS (https://www.lipidmaps.org) are shown below them, with each number corresponding to an n value of 1 or 15, as indicated in the figure. Two models have been proposed for how protein-bound ceramides bind to corneocyte envelope proteins

The skin’s top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.

Ceramides are a type of lipid that are found in abundance in the top layer of the skin, called the stratum corneum...

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