serotonin tagged posts

New findings from Flinders University have demonstrated a molecular link between COVID-19 and serotonin cells in the gut.

The research could help provide further clues to what could be driving COVID-19 infection and disease severity and supports previous evidence that antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), could reduce the severity of COVID symptoms.

COVID-19 displays an array of symptoms, which can regularly include gastrointestinal issues such as diarrhoea. Recent research has indicated that these gut symptoms in COVID-19 patients worsen with the severity of the disease, and this is linked to heightened gut-derived serotonin, released to cause gut dysfunction, increasing the body’s immune response and potentially worsening patient outcomes.

Dopamine, serotonin involved in sub-second perception, cognition...

Popular protein great for increasing muscle mass, but could reduce your life-span – researchers say to vary protein intake. Researchers have examined whether there are any ongoing ramifications or potential side-effects from long-term high protein intake or from consuming certain types of amino acids.

Led by academics from the University of Sydney’s Charles Perkins Centre, Professor Stephen Simpson and Dr Samantha Solon-Biet, suggests that while delivering muscle-building benefits, excessive consumption of branched-chain amino acids (BCAAs) may reduce lifespan, negatively impact mood and...

Highlights
•Enterochromaffin (EC) cells are excitable and express voltage-gated ion channels
•EC cells use sensory receptors to detect irritants, metabolites, and catecholamines
•EC cell activation leads to voltage-gated Ca2+ channel-dependent serotonin release
•EC cells modulate sensory nerves via serotonin receptors and synaptic connections

Cells that alert nervous system to intestinal trouble could provide new target for gastrointestinal treatments. Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study led by UC San Francisco scientists. “These cells are sensors, like a window looking into the contents of the gut,” said James Bayrer, MD, PhD, an assistant professor of pediatrics at UCSF.

Usin...