Severe COVID-19 tagged posts

Study links Severe COVID-19 to Increase in Self-Attacking Antibodies

An illustration of antibodies among blood cells.
SciePro/Shutterstock.com

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies than people without COVID-19, according to a new study. Autoantibodies can be early harbingers of full-blown autoimmune disease. “If you get sick enough from COVID-19 to end up in the hospital, you may not be out of the woods even after you recover,” said PJ Utz, MD, professor of immunology and rheumatology at Stanford Medicine.

Utz shares senior authorship of the study, which will be published Sept...

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Pick up the pace! Slow Walkers Four Times more likely to Die from COVID-19, study finds

Slow walkers are almost four times more likely to die from COVID-19, and have over twice the risk of contracting a severe version of the virus, according to a team of researchers from the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre led by Professor Tom Yates at the University of Leicester.

The study of 412,596 middle-aged UK Biobank participants examined the relative association of body mass index (BMI) and self-reported walking pace with the risk of contracting severe COVID-19 and COVID-19 mortality.

The analysis found slow walkers of a normal weight to be almost 2.5 times more likely to develop severe COVID-19 and 3.75 times more likely to die from the virus than normal weight fast walkers.

Professor Yates, Lead Researcher for the stud...

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Strong Activation of Anti-bacterial T cells linked to Severe COVID-19

Illustration of T cells fighting virus
Illustration: Getty Im“MAIT cell activation and dynamics associated with COVID-19 disease severity,” Parrot, T., Gorin, J. B., Ponzetta, A., Maleki, K. T., Kammann, T., Emgård, J., Perez-Potti, A., Sekine, T., Rivera-Ballesteros, O., the Karolinska COVID-19 Study Group, Gredmark-Russ, S., Rooyackers, O., Folkesson, E., Eriksson, L. I., Norrby-Teglund, A., Ljunggren, H. G., Björkström, N. K., Aleman, S., Buggert, M., Klingström, J., Strålin, K., and Sandberg, J. K., Science Immunology, online 28 september, 2020, doi: 10.1126/sciimmunol.abe1670ages

A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal...

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