age-specific longevity loci. Body weight associates with longevity, as does litter size, through its effect on
body weight. Mendelian randomization in humans recapitulated these relationships between early growth
and life span. Gene expression analyses, cross-species integration, and Caenorhabditis elegans life-span
experiments highlight candidate longevity genes and provide a resource for further investigation.
Researchers from the National Institute on Aging (NIA)-funded Interventions Testing Program recently reported the discovery of multiple candidate genes that influence longevity...
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