Short-chain fatty acids tagged posts

New Study shows how Salmonella Tricks Gut Defenses to cause Infection

3D illustration of Salmonella bacteria in yellow green color
Salmonella infects the small intestine and alters the colon environment

A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present. The research, published in the Proceedings of the National Academy of Sciences, explains how the pathogen tricks the gut environment to escape the body’s natural defenses.

The digestive system is home to trillions of bacteria, many of which produce short-chain fatty acids (SCFAs) that help fight harmful pathogens. But Salmonella manages to grow and spread in the gut, even though these protective compounds are present. The study asks: How does Salmonella get around this defense?

“We knew that Salmonella invades the small intestine, although it is not ...

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Anti-Tumor Agent from the Intestine

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists reveals. The findings could help improve cancer therapies.

It is believed to be involved in the development of chronic inflammatory intestinal diseases, to trigger diabetes, to be responsible for obesity, even neurological diseases such as multiple sclerosis and Parkinson’s could have their causes here — not to mention depressions and autistic disorders. We are talking about the microbiome — the vast collection of bacteria in the human gut. It is estimated that each person carries around 100 trillion bacterial cells in their digestive tract, belonging to several thousand species.

Scientists at the Universities of Würzburg and Marburg have now succeeded for ...

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