Rice University bioengineers use a magnetic field to activate nanoparticle-attached baculoviruses in a tissue. The viruses, which normally infect alfalfa looper moths, are modified to deliver gene-editing DNA code only to cells that are targeted with magnetic field-induced local transduction.
Credit: Laboratory of Biomolecular Engineering and Nanomedicine/Rice University
Experimental therapy could repair mutations that cause genetic diseases. Bioengineers have combined a virus that infects moths with magnetic nanoparticles to create a potential new therapy for inherited genetic diseases like muscular dystrophy, sickle cell, cystic fibrosis, spinal muscular atrophy and some forms of cancer.
Rice University bioengineer Gang Bao has combined magnetic nanoparticles with a viral container drawn ...
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