signatures associated with different mortality and morbidity risk tagged posts

Paola Sebastiani, Bharat Thyagarajan, Fangui Sun, Nicole Schupf, Anne B. Newman, Monty Montano, Thomas T. Perls. Biomarker signatures of aging. Aging Cell, 2017; DOI: 10.1111/acel.12557

Levels of specific biomarkers can be combined to produce patterns that signify how well a person is aging and his or risk for future aging-related diseases, according to a new study by researchers at the Boston University Schools of Public Health and Medicine and Boston Medical Center. The study used biomarker data collected from the blood samples of almost 5,000 participants in the Long Life Family Study, funded by the National Institute on Aging (NIA) at the National Institutes of Health (NIH).

A large number – about half – had an average “signature,” or pattern, of 19 biomarkers...