Two different aspects of fat: left, mature human fat cells grown in a Petri dish (green: lipid droplets); right, a section of mouse fat tissue with in the middle, a blood vessel (red circle) surrounded by Aregs (arrows), newly discovered cells capable of suppressing adipogenesis. Credit: Bart Deplancke/EPFL
A study has revealed a new cell type that resides in the body’s fat depots where it can actively suppress fat cell formation. This discovery was made using single-cell transcriptomics and opens entirely new avenues to combat obesity and related diseases such as diabetes.
Adipogenesis – the formation of mature fat cells from their precursor cells – has been linked to obesity and related health problems such as cardiovascular disease and type-2 diabetes...
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