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A Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fibre in the gut can protect against allergic skin disease. The research could potentially lead to novel treatments to prevent or treat allergies.

Professor Ben Marsland from the Central Clinical School’s Department of Immunology, together with Swiss colleagues at the University Hospital of Lausanne (CHUV), showed that the fermentation of fibre in the gut by bacteria and subsequent production of short-chain fatty acids (SCFAs), in particular butyrate, protected against atopic dermatitis in mice.

The research was published today in Mucosal Immunology.

While it is well established that the gut microbiome shapes the immune system, the influence it has on the skin is le...

Early findings indicate eating the fruit could help with skin allergies

In a study done with mice and published earlier this month in the journal Nutrients, researchers found that a diet high in black raspberries reduced inflammation from contact hypersensitivity – a condition that causes redness and inflammation in the skin.

“A lot of times, treatments are directly applied to the skin – things like steroids,” said Steve Oghumu, senior author on the paper and an assistant professor of pathology at The Ohio State University.

“And it was interesting that the mere consumption of a fruit can achieve the same effects.”

The researchers put a group of mice on a ...