sleep-deprived tagged posts

Human-approved Medication Brings Back ‘Lost’ Memories in Mice

Human-approved medication brings back 'lost' memories in mice
High magnification image showing part of the mouse hippocampus in which a sparse population of neurons encoding a specific learning event are labelled in red. Neurons that are not activated by the learning event are shown in blue. | Illustration Havekes Lab, University of Groningen

Students sometimes pull an all-nighter to prepare for an exam. However, research has shown that sleep deprivation is bad for your memory. Now, University of Groningen neuroscientist Robbert Havekes discovered that what you learn while being sleep deprived is not necessarily lost, it is just difficult to recall.

Together with his team, he has found a way to make this “hidden knowledge” accessible again days after studying while sleep-deprived using optogenetic approaches, and the human-approved asthma drug...

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Fruit fly Brains shed Light on why we get Tired when we stay up Too Late

When the sleep-drive neurons turn on, it puts the fruit flies to sleep. And when the sleep-drive neurons are turned off in well-rested flies, the flies awaken. Credit: Johns Hopkins Medicine

When the sleep-drive neurons turn on, it puts the fruit flies to sleep. And when the sleep-drive neurons are turned off in well-rested flies, the flies awaken. Credit: Johns Hopkins Medicine

Studying fruit flies, whose sleep is remarkably similar to that in people, Johns Hopkins researchers say they’ve identified brain cells in charge of so-called sleep drive that becomes more active the longer flies are kept awake. The same mechanism also plays a role in putting the flies to sleep and keeping them that way. The findings may offer insight into human sleep disorders and open up new strategies to promote long-lasting sleep for those with chronic insomnia who don’t respond to available sleep drugs, they say.

In their search for sleep-regulating cells, Wu’s team used genetic engineering to tur...

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