SNORA13 tagged posts

Study identifies RNA molecule that Regulates Cellular Aging

SNORA13 (red) in the nucleus of senescent human cells
This shows SNORA13 (red) in the nucleus of senescent human cells within a specialized structure called the nucleolus where ribosomes are assembled. DNA is stained in blue.

A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division. The findings, published in Cell, could one day lead to new interventions for a variety of conditions associated with aging, including neurodegenerative and cardiovascular diseases, diabetes, and cancer, as well as new therapies for a collection of diseases known as ribosomopathies.

“There is great interest in reducing senescence to slow or reverse aging or aging-associated diseases...

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