Social Anxiety tagged posts

SSRIs and CBT lead to Changes in Brain

SSRIs and CBT lead to changes in brain

Neurochemical changes in the brain differ among patients with social anxiety treated using both SSRIs and CBT, compared to those treated using only CBT. While the combined treatment involving the medicine blocked the serotonin transporters, availability of such transporters increased in patients who only received CBT.

Treatment using selective serotonin reuptake inhibitors, or SSRIs, is effective for depression and anxiety and can be even more effective when combined with cognitive behavioral therapy, or CBT. However, it has not been established which mechanisms in the brain clarify the clinical improvement.

In a double-blind positron emission tomography (PET) study, researchers at Uppsala University investigated people with social anxiety and looked at how serotonin and dopamin...

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The effects of Oxytocin on Social Anxiety depend on Location, location, location

Mouse
Working with California mice, UC Davis researches showed that the “love hormone” oxytocin can sometimes have antisocial effects depending on where in the brain it is made. (Mark Chappell/UC Riverside)

Finding a better route to treating social anxiety disorder may lie in another part of the brain, researchers suggest. The findings of the study show that oxytocin produced in the BNST increases stress-induced social anxiety behaviors in mice. This may provide an explanation as to why oxytocin can sometimes have antisocial effects.

Studies have long suggested that oxytocin – a hormone that can also act as a neurotransmitter – regulates prosocial behavior such as empathy, trust and bonding, which led to its popular labeling as the “love hormone...

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