spike protein tagged posts

Spike Mutations that Help SARS-CoV-2 Infect the Brain Discovered

SARS-CoV-2 , COVID-19
Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

Scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system. The findings may help scientists understand its neurological symptoms and the mystery of “long COVID,” and they could one day even lead to specific treatments to protect and clear the virus from the brain.

The new collaborative study between scientists at Northwestern University and the University of Illinois-Chicago uncovered a series of mutations in the SARS-CoV-2 spike protein (the outer part of the virus that help...

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As COVID Cases Rise again, what do I need to know about the New FLiRT Variants?

As COVID cases rise again, what do I need to know about the new FLiRT variants?
The proportion of COVID cases caused by FLiRT subvariants is rising in NSW. Credit: NSW Health

We’ve now been living with COVID for well over four years. Although there’s still much to learn about SARS-CoV-2 (the virus that causes COVID) at least one thing seems clear: it’s here to stay.

From the original Wuhan variant, to delta, to omicron, and several others in between, the virus has continued to evolve.

New variants have driven repeated waves of infection and challenged doctors and scientists seeking to understand this changing virus’ behavior.

Now, we are faced with a new group of variants, the so-called “FLiRT” variants, which appear to be contributing to a rising wave of COVID infections around Australia and elsewhere...

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COVID-19 Virus enters the Brain, research strongly suggests

Illustration of a storm in your brain from COVID-19

The S1 protein likely causes the brain to release inflammatory products causing a storm in the brain, researchers said. Alice Gray

A new study shows how spike protein crosses the blood-brain barrier. The SARS-CoV-2 virus, like many viruses before it, is bad news for the brain. In a new study, researchers found that the spike protein, often depicted as the red arms of the virus, can cross the blood-brain barrier in mice. The spike proteins alone can cause brain fog. Since the spike protein enters the brain, the virus also is likely to cross into the brain.

In a study published Dec.16 in Nature Neuroscience, researchers found that the spike protein, often depicted as the red arms of the virus, can cross the blood-brain barrier in mice.
This strongly suggests that SARS-CoV-2, the cause ...

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Diagnostic Biosensor quickly detects SARS-CoV-2 from Nasopharyngeal Swabs

An artist’s rendering above shows a new test that quickly detects SARS-CoV-2 (spheres) through binding to antibodies (Y-shapes) on a field-effect transistor.
Adapted from ACS Nano 2020, DOI: 10.1021/acsnano.0c02823

Researchers have developed a field-effect transistor-based biosensor that detects SARS-CoV-2 in nasopharyngeal swabs from patients with COVID-19, in less than one minute.

According to many experts, early diagnosis and management are critical for slowing the spread of SARS-CoV-2, the new coronavirus that causes COVID-19. Therefore, the race is on to develop diagnostic tests for the virus that are faster, easier and more accurate than existing ones...

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