SSRIs tagged posts

New insights into the opposing actions of serotonin-producing nerve fibres in mice could lead to drugs for treating addictions and major depression.

Scientists in Japan have identified a nerve pathway involved in the processing of rewarding and distressing stimuli and situations in mice.

The new pathway, originating in a bundle of brain stem nerve fibres called the median raphe nucleus, acts in opposition to a previously identified reward/aversion pathway that originates in the nearby dorsal raphe nucleus...

Neurochemical changes in the brain differ among patients with social anxiety treated using both SSRIs and CBT, compared to those treated using only CBT. While the combined treatment involving the medicine blocked the serotonin transporters, availability of such transporters increased in patients who only received CBT.

Treatment using selective serotonin reuptake inhibitors, or SSRIs, is effective for depression and anxiety and can be even more effective when combined with cognitive behavioral therapy, or CBT. However, it has not been established which mechanisms in the brain clarify the clinical improvement.

In a double-blind positron emission tomography (PET) study, researchers at Uppsala University investigated people with social anxiety and looked at how serotonin and dopamin...