stem cell therapy tagged posts

Space: A New Frontier for Exploring Stem Cell Therapy

Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease, two Mayo Clinic researchers say. The research analysis by Fay Abdul Ghani and Abba Zubair, M.D., Ph.D., published in NPJ Microgravity, finds microgravity can strengthen the regenerative potential of cells. Dr. Zubair is a laboratory medicine expert and medical director for the Center for Regenerative Biotherapeutics at Mayo Clinic in Florida. Abdul Ghani is a Mayo Clinic research technologist. Microgravity is weightlessness or near-zero gravity.

“Studying stem cells in space has uncovered cell mechanisms that would otherwise be undetected or unknown within the presence of normal gravity,” says Dr. Zubair...

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Treatment for Type-2 Diabetic Heart Disease

Discovery for treatment of heart disease in type-2 diabetics
Graphical abstract. Credit: Diabetologia (2021). DOI: 10.1007/s00125-021-05405-7

University of Otago researchers have discovered one of the reasons why more than 50% of people with type 2 diabetes die from heart disease. And perhaps more significantly, they have found how to treat it.

Associate Professor Rajesh Katare, of the Department of Physiology, says it has been known that stem cells in the heart of diabetic patients are impaired. While stem cell therapy has proved effective in treating heart disease, it is not the case in diabetic hearts.

It has not been known why; until now.
It comes down to tiny molecules called microRNA which control gene expression.

“Based on the results of laboratory testing, we identified the number of microRNAs that are impaired in stem cells of...

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