steroids tagged posts

UC Davis Health study finds potential keys to reversing bone loss

Researchers uncover a key protein and a promising strategy to prevent bone damage from steroids

The rheumatology and orthopedic researchers discovered that a protein called Basigin, which gets activated in stem cells when people take steroids, is a key reason why bones weaken and blood vessels in bone tissue become abnormal. By blocking Basigin, they were able to protect and even restore bone health in mice, suggesting a promising new treatment path.

Their findings were published in Nature Communications.

“This research is a major step forward in understanding how steroid treatments affect bone health,” said Thomas H. Ambrosi, assistant professor in the Department of Orthopedic Surgery and co-corresponding author of the study...

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New AI model can estimate a person’s true biological age from five drops of blood

Top Left: A small blood sample is analyzed to measure 22 key steroids, and the data is fed into an AI system to calculate biological age. Top Right: The AI-predicted biological age (BA) shows a general correlation with chronological age (CA), but individual differences widen over time. Bottom: Using the metaphor of a “river widening as it flows downstream,” the illustration visualizes how biological age evolves with the passage of time. Credit: Zi Wang

We all know someone who seems to defy aging—people who look younger than their peers despite being the same age. What’s their secret? Scientists at Osaka University (Japan) may have found a way to quantify this difference...

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