stress tagged posts

Anatomy of hippocampal circuit into which new neurons integrate. Neurogenesis is localized to the dentate gyrus (DG) region, where only excitatory granule cells are continually produced throughout life. The DG has a complex local circuitry, with both inhibitory interneurons and excitatory feedback neurons (mossy cells) participating in the network’s behavior. Granule cells in the DG project to the CA3 region, which in addition to a robust recurrent connection then projects to the CA1 region. The CA1 then projects back to the entorhinal cortex and subiculum regions, closing the “hippocampal loop.”

Stressful events result in epigenetic modifications within immediate-early genes in hippocampus neurons...

Alzheimer’s Association International Conference has 5 tips to guard your brain against memory loss:

GET BETTER SHUT-EYE
Studies of >6,000 people linked poor sleep quality, especially sleep apnea to mild cognitive impairment >> raises the risk of later Alzheimer’s. Other research showed poor sleep can spur amyloid, a hallmark of Alzheimer’s. “Sleep disorders are so common, and we think many are quite treatable.”

EXERCISE YOUR GRAY MATTER
Seniors often are advised to work crossword puzzles, take music lessons or learn a new language to keep the brain engaged. The protective effects of learning may start decades earlier in life. In Sweden, researchers at the Karolinska Institute unearthed school report cards and work histories of >7,000 older adults...