striatum tagged posts

Insulin in the Brain influences Dopamine Levels

In the human brain, the hormone insulin also acts on the most important neurotransmitter for the reward system, dopamine. This was shown by researchers from the German Center for Diabetes Research (DZD) in Tübingen. Insulin lowers the dopamine level in a specific region of the brain (striatum *) that regulates reward processes and cognitive functions, among other things. This interaction can be an important driver of the brain’s regulation of glucose metabolism and eating behavior. The study has now been published in the Journal of Clinical Endocrinology & Metabolism.

Worldwide, more and more people are developing obesity and type 2 diabetes. Studies show that the brain plays an important role in causing these diseases...

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Heavy Cannabis use Associated with Reduced Dopamine release in Brain

Marijuana plant (stock image). Evidence of a compromised dopamine system has been found in heavy users of marijuana. Credit: © Vasily Merkushev / Fotolia

Marijuana plant (stock image). Evidence of a compromised dopamine system has been found in heavy users of marijuana. Credit: © Vasily Merkushev / Fotolia

Evidence of a compromised dopamine system has been found in heavy users of marijuana. Effect similar to other addictions. Lower dopamine release was found in the striatum – involved in working memory, impulsive behavior, and attention. Previous studies have shown that addiction to other drugs of abuse, such as cocaine and heroin, have similar effects on dopamine release, but such evidence for cannabis was missing until now.

“In light of the more widespread acceptance and use of marijuana, especially by young people, we believe it is important to look more closely at the potentially addictive effects of cannabis on key regions of the brai...

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A Nap to Recap: How Reward, Daytime Sleep Boost Learning

 

A new study suggests that receiving rewards as you learn can help cement new facts and skills in your memory, particularly when combined with a daytime nap. The findings from the University of Geneva reveal that memories associated with a reward are preferentially reinforced by sleep. Even a short nap after a period of learning is beneficial.

“Rewards may act as a kind of tag, sealing information in the brain during learning,” says lead researcher Dr Kinga Igloi from the University of Geneva. “During sleep, that information is favourably consolidated over information associated with a low reward and is transferred to areas of the brain associated with long-term memory.”

“Our findings are relevant for understanding the devastating effects that lack of sleep can have on achievement,” s...

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