stroke tagged posts

Protein aggregation inhibitor shows lower levels of cell death and paralysis in mice with acute strokes.

Stroke kills millions, but Osaka researchers have unveiled GAI-17, a drug that halts toxic GAPDH clumping, slashes brain damage and paralysis in mice—even when given six hours post-stroke—and shows no major side effects, hinting at a single therapy that could also tackle Alzheimer’s and other tough neurological disorders.

Stroke is said to be the se...

Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol increases oxidative stress, disrupts nitric oxide signaling, raises vasoconstrictive peptide production, and diminishes clot-dissolving capacity in human brain microvascular endothelial cells.

Erythritol has become a fixture in the ingredient lists of protein bars, low-calorie beverages, and diabetic-friendly baked goods. Its appeal lies in its sweetness-to-calorie ratio, roughly 60–80% as sweet as sucrose with a tiny fraction of the energy yield, and its negligible effect on blood glucose...

Shandong researchers suggest that edible and medicinal fungi contain bioactive components with therapeutic potential for central nervous system (CNS) diseases. Findings offer evidence for the potential of these fungi to serve as novel pharmaceuticals or functional foods in the treatment of CNS diseases.

Central nervous system (CNS) diseases involve complex pathophysiology, gradual symptom onset, and significant challenges in therapeutic evaluation...

One-minute, short bursts of high-intensity interval training for 19 minutes may be more effective for improving fitness among people six months or more after a stroke than traditional, 20–30 minutes of moderate-intensity exercise sessions, according to research published today in the journal Stroke.

“This study shows that people with stroke can also benefit from high-intensity interval training,” said Kevin Moncion, Ph.D., a physiotherapist who led this study as part of his doctoral studies at McMaster University in Hamilton, Ontario, Canada. “With the right support and guidance, stroke survivors can safely and effectively engage in high-intensity interval training, significantly improving their overall health and recovery.”

The multi-site tria...