sugar tagged posts

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease. In affected patients, the immune system attacks the body’s own tissue and the consequences are, for example, chronic inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis, type 1 diabetes and chronic inflammation of the thyroid gland.

New targets for therapy

The underlying molecular mechanisms that promote autoimmune diseases are multilayered and complex...

The average American eats roughly 22 teaspoons of added sugar a day – more than three times the recommended amount for women and more than double the recommended amount for men.

Although this overconsumption is known to contribute to Type 2 diabetes and other disorders, the exact ways in which eating too much sugar sets the stage for metabolic diseases on a cellular level has been less clear. Now, a team led by Van Andel Institute scientists has found that surplus sugar may cause our cellular powerplants – mitochondria – to become less efficient, reducing their energy ouput.

The findings, published today in Cell Reports, highlight the cellular implications of excessive sugar consumption and provide an important new model to study the initial metabolic events that may contribute ...

Researchers at the University of Texas at Dallas have found that two types of non-small cell lung cancer metabolize glucose — a type of sugar — differently. A glucose transporter called GLUT1, shown in green, is much more prevalent in lung squamous cell carcinoma cells (right) in comparison to lung adenocarcinoma cells (left). The findings, published in the online journal Nature Communications, may aid the development of new lung cancer therapies targeted at inhibiting GLUT1. Credit: University of Texas at Dallas

In a new study, The University of Texas at Dallas scientists have found that some types of cancers have more of a sweet tooth than others...

A new Yale study shows the brain responds to taste and calorie counts in fundamentally different ways. And only one of these responses explains why most New Years’ resolutions have already disappeared under a deluge of Boston Crème Pies. It’s the brain’s desire for calories – not sweetness – that dominates our desire for sugars.

“It turns out the brain actually has two segregated sets of neurons to process sweetness and energy signals,” said Ivan de Araujo of the John B. Pierce Laboratory. “If the brain is given the choice between pleasant taste and no energy, or unpleasant taste and energy, the brain picks energy.”

Both sweet taste and nutrient value register in the striatum, an ancient region of the brain involved in processing rewards...