New imaging potential: Standard resolution (left) compared to (center, right) high resolution and super-resolution obtained with the chip-based technique. Credit: Bielefeld University/Robin Diekmann
Physicists have developed a photonic chip that makes it possible to carry out super-resolution light microscopy, ie ‘nanoscopy,’ with conventional microscopes. In nanoscopy, the position of single fluorescent molecules can be determined with a precision of just a few nano-meters (millionth of a millimeter). This information can be used to produce images with a resolution of ~20 to 30 nm, and thereby 10X that of conventional light microscopy. Until now, this method has required the use of expensive special instruments...
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