SYK tagged posts

Brain Discovery holds key to Boosting Body’s Ability to Fight Alzheimer’s, MS

John Lukens, PhD, is investigating how brain injury disrupts drainage of deleterious waste from the brain and how that may contribute to Alzheimer's disease.
John Lukens, PhD, is leading important research that could transform how we approach Alzheimer’s and other neurological diseases.

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system’s responses to Alzheimer’s disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body’s ability to fight those and other devastating neurological diseases.

The molecule the researchers identified, called a kinase, is crucial to both removing plaque buildup associated with Alzheimer’s and preventing the debris buildup that causes MS, the researchers found. It does this, the researchers showed, by directing the activity of brain cleaners called microglia...

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