T helper cells tagged posts

Dietary Fat may impact Severity and Duration of Autoimmune Flare-ups

PA Ameliorates CNS Autoimmunity via Induction of Treg Cells in the Small Intestine

PA Ameliorates CNS Autoimmunity via Induction of Treg Cells in the Small Intestine

Adjusting length of fatty acids consumed by mice altered the function of T helper cells in the gut – either intensifying or alleviating symptoms in an animal model of the autoimmune disease (i.e., multiple sclerosis).

A team compared in mice the effects of short-chain fatty acids, which are solely metabolized by gut bacteria and are typically found in fiber-rich diets, with the effects of long-chain fatty acids, the most abundant component of western diets. They found that long-chain fatty acids, such as lauric acid and palmitic acid, promoted the development and release of proinflammatory T cells from the intestinal wall to other areas in the body, including the brain...

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