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    New Clue into the Curious Case of our Aging Immune System

    August 16, 2024, Categories  Biology/Biotechnology, Health/Medical

    Pictured are the cells that form clusters in the thymus with age. On the left, the thymus from a two-month-old mouse has few age-associated (in blue) clusters. On the right, the thymus from a 24-month-old mouse shows many clusters. Researchers have found these clusters form ‘scars’ in the thymus which prevent the organ from restoring itself after damage.

    A WEHI study could help solve a long-standing mystery into why a key immune organ in our bodies shrinks and loses its function as we get older.

    The thymus is an organ essential for good health due to its ability to produce special immune cells that are responsible for fighting infections and cancer.

    In a world-first, researchers have uncovered new cells that drive this ageing process in the thymus — significant findings that could unlock a way to restore function in the thymus and prevent our immunity from waning as we age.

    At a glance

    The thymus is an organ essential for our immune defence but it shrinks and weakens as we get older. The reason for this loss remains a long-standing mystery.

    A new study has been able to visualise, for the first time, how two cell types d...

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