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E coli ‘Anchors’ provide novel way to Hijack Superbugs

type 1 and P fimbriae of uropathogenic Escherichia coli, the major causative agent of urinary tract infections in humans.

type 1 and P fimbriae of uropathogenic Escherichia coli, the major causative agent of urinary tract infections in humans.

A way has been found to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant ‘superbugs’. The Austalian researchers have uncovered what may be an Achilles heel on the bacteria cell membrane that could act as a potential novel drug target. Almost every second woman suffers from a urinary tract infection, UTI during her lifetime, mostly caused by E. coli. It travels along the urethra to the bladder where it triggers painful infections.

In order to infect the bladder (which is constantly being flushed out with urine), the bacteria have developed nanofilaments which effectively anchor the bacteria to the ...

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