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    SARS-CoV-2 infects testicular cells and uses cellular machinery to replicate, study finds

    August 23, 2025, Categories  Biology/Biotechnology, Health/Medical

    SARS-CoV-2 infects testicular cells and uses cellular machinery to replicate and form
    (A–D) Photomicrographs of testicular sections of animals from CG and IG submitted to CD68 (A, B) and CD163 (C, D) immunohistochemistry. Nuclear staining with hematoxylin. In (A) the interstitial tissue shows a few CD68+ macrophages (arrows) in comparison to the high incidence of these cells observed in IG (B). In (C, D), CD163-immunolabeled macrophages are seen (arrows); however, in (D), note the high incidence of these macrophages (arrows) in comparison to CG. (E, F) The number of CD68 and CD163-immunolabeled macrophages per µm2 of interstitial tissue is higher in IG in comparison to CG. (G) Western blot analysis of MIF levels in testicular extracts shows strong bands at 9KDa in IG in comparison to CG. β-tubulin signal is observed in both groups...
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