Total synthesis of micrococcin P1 and thiocillin I enabled by Mo(vi) catalyst. Chemical Science, 2019; DOI: 10.1039/C8SC04885A
University of Colorado Boulder chemistry researchers have developed a novel way to synthesize and optimize a naturally-occurring antibiotic compound that could one day be used to fight lethal drug-resistant infections such as Staphylococcus aureus, commonly known as MRSA.
Antibiotic-resistant infections afflict over 2 million people annually and result in over 23,000 deaths in the U.S. each year, according to the Centers for Disease Control and Prevention (CDC). A 2018 study by the CDC’s European counterpart found that drug-resistant superbugs were responsible for 33,000 deaths across Europe in 2015.
Researchers have previously identified thiopepti...
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