(A) Schematic of TEP-only sTOs.
(B) Representative IF images of KRT8 (green) and KRT5 (magenta) in day 16–22 TEPs and week 2 TEP-only sTOs (TEPs, n = 2 indepdendent experiment (ind. exp.), 2 hPSC lines; sTOs, n = 3 ind. exp., 2 hPSC lines).
(C–H) FC plots and quantification of EPCAM/HLA-DR (C and D), EPCAM/CD205 (E and F), and EPCAM/GFP (G and H) expression in day 16–22 TEPs and week 2 TEP-only sTOs.
(I) tSNE plots of EPCAM, HLA-DR, CD205, and GFP expression in 16–22 TEPs and week 2 TEP-only sTOs, n = 3 ind. exp., 1 hPSC line.
Plots show percentage of the mean; data are shown as mean ±
± SEM.
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