Time-restricted feeding tagged posts

Rhythmic Eating Pattern preserves Fruit Fly Muscle Function under Obese Conditions

Fig. 7
Proposed mechanism of TRF in Drosophila skeletal muscle under obesogenic challenges.

Obese fruit flies are the experimental subjects in a Nature Communications study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels.

Interestingly, studies in various animal models have shown that time-restricted feeding — a natural non-pharmaceutical intervention — protects against obesity, aging and circadian disruption in peripheral tissues such as skeletal muscle. However, the mechanisms underlying those benefits were not known.

In fruit flies — scientifically known as Drosophila melanogaster — obese Drosophila that are subje...

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Why Late-Night Eating leads to Weight Gain, Diabetes

The science behind the study is underpinned by research done at Northwestern more than 20 years ago that found a relationship between the internal molecular clock and body weight, obesity and metabolism in animals.

Health benefits come from eating during the daytime, demonstrating a potential link to energy release. Northwestern Medicine scientists have uncovered the mechanism behind why eating late at night is linked to weight gain and diabetes.

The connection between eating time, sleep and obesity is well-known but poorly understood, with research showing that over-nutrition can disrupt circadian rhythms and change fat tissue.

New Northwestern research has shown for the first time that energy release may be the molecular mechanism through which our internal clocks control energ...

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