TP53 gene mutation tagged posts

This is a model of the TP53 sensor. The Sensor is symbolized as a ‘thermometer’ that displays the TP53 status in the cell. Credit: TU Dresden, Frank Buchholz

Molecular ‘detector’ recognizes most frequent cancer-mutation in cells, TP53 gene, and initiates to kill them. The alert goes on if the TP53 gene is mutated in cells. The molecular smoke detector works like a TP53 sensor, which monitors the correct function of the gene. A non-functional TP53 gene is going to activate the sensor, which initiates cell death. Results from this study from the research team of Prof. Frank Buchholz are now published in the journal Nature Communications.

Cancer is caused by changes in the human genome...