treating periodontal disease tagged posts

Disarming a Blood-Clotting Protein Prevents Gum Disease in mice

Compared to healthy volunteers (left), gum tissue from people with severe periodontal disease (right) shows high levels of fibrin (magenta). Lakmali Silva, NIDCR

Human and animal study offers insight into treating periodontal disease and other inflammatory disorders. Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health. Drawing on animal and human data, the researchers found that buildup of the protein, called fibrin, triggers an overactive immune response that damages the gums and underlying bone...

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