TRF tagged posts

Obese fruit flies are the experimental subjects in a Nature Communications study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels.

Interestingly, studies in various animal models have shown that time-restricted feeding — a natural non-pharmaceutical intervention — protects against obesity, aging and circadian disruption in peripheral tissues such as skeletal muscle. However, the mechanisms underlying those benefits were not known.

In fruit flies — scientifically known as Drosophila melanogaster — obese Drosophila that are subje...

Researchers found that in mice how much they ate and when altered the nature of their gut microbiome: too much food too frequently resulted in poorer microbial and metabolic health.

An estimated 500 to 1,000 bacterial species reside in each person’s gut, perhaps numbering 100,000 trillion microorganisms...