Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University’s Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.
Cellular immunotherapies that specifically target malignant tumors are thought to be a promising approach in cancer medicine. However, a basic requirement for this kind of targeted immunotherapy is to identify target molecules that are found exclusively on the tumor cells and are recognized by the immune system.
Malignant gliomas are incurable brain tumors that spread in the brain and cannot be completely removed by surgery...
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