type 2 diabetes tagged posts

New Study identifies Connection between Diabetes Medications, Multiple Sclerosis

A new study found that anti-hyperglycemic medications used to treat Type 2 diabetes resulted in an increased risk of multiple sclerosis for people older than 45, particularly among women.

A new University of Arizona Health Sciences study found that people older than 45yo whose Type 2 diabetes was treated with anti-hyperglycemic medications had an increased risk of multiple sclerosis, particularly among women, while anti-hyperglycemic exposure in people younger than 45 reduced that risk.

“Our findings reinforce the need for a precision medicine approach to preventing MS in these vulnerable populations,” said lead researcher Kathleen Rodgers, PhD, associate director of translational neuroscience at the Center for Innovation in Brain Science.

Multiple sclerosis (MS) is an unpredicta...

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High-Fat Diets Trigger Inflammatory Immune Cell Generation in Bone

High-fat diets drive the production of inflammatory immune cells in the bone  marrow of mice
High-fat diets trigger inflammatory immune cell generation in bone

A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice. The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity.

An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many immune cells, including monocytes, are produced in the bone marrow, which is very sensitive to environmental changes. Scientists have already shown that fat cells in the bone marrow rapidly expand in response to a high-fat diet.

“We wanted to know ...

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Rhodiola rosea root might be beneficial for Managing Type 2 Diabetes

UCI-led study shows Rhodiola rosea root might be beneficial for managing type 2 diabetes
“Characterized by insulin resistance, type 2 diabetes is the most prevalent endocrine disease in the world today, responsible for more than $200 billions of healthcare costs annually in the U.S. alone,” says corresponding author Mahtab Jafari, UCI professor of pharmaceutical sciences. “Our findings show Rhodiola rosea might be beneficial for treating this disease and is a good candidate for further investigation.” Steve Zylius / UCI

Botanical extract shows promise as an alternative to drug therapy. A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

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Type 2 Diabetes Accelerates Brain Aging and Cognitive Decline

Aging effects on the brain, further exacerbated in type 2 diabetes. Image credit: Lilianne Mujica-Parodi (CC BY 4.0)

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

The authors evaluated the relationship between typical brain aging and that seen in type 2 diabetes, and observed that type 2 diabetes follows a similar pattern of neurodegeneration as aging, but which progresses faster. One important implication of this finding is that even typical brain aging may reflect changes in the brain’s regulation of glucose by insulin.

The results further suggest that by the time type 2 diabetes is formally diagnosed, the...

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