type 2 diabetes tagged posts

A team of scientists from Scripps Research has conducted promising early tests of a new strategy that might one day be used to prevent or treat type 2 diabetes.

The scientists, whose results are reported in Nature Communications, tested an experimental compound called IXA4 in obese mice. They showed that the compound activates a natural signaling pathway that protects the animals from harmful, obesity-driven metabolic changes that would normally lead to diabetes.

“We were able to activate this pathway in both the liver and the pancreas with this one compound, and that added up to a significant overall improvement in metabolic health of obese animals,” says Scripps Research’s Luke Wiseman, Ph.D.

“This is the first time anyone has shown that a small molecule activating this pat...

Monash University, Australia scientists have discovered an enzyme that is key to why exercise improves our health. Importantly this discovery has opened up the possibility of drugs to promote this enzyme’s activity, protecting against the consequences of aging on metabolic health, including type 2 diabetes.

The proportion of people worldwide over 60 years old will double in the next three decades and by 2031, more than six million Australians will be over 65 years old. The incidence of type 2 diabetes increases with age so this aging population will also result in an increased incidence of the disease globally.

One of the main reasons for the increased prevalence of type 2 diabetes with age i...

Altered function of the red blood cells leads to vascular damage in type 2 diabetes. Results from a new study in cells from patients with type 2 diabetes and mice show that this effect is caused by low levels of an important molecule in the red blood cells. The study by researchers at Karolinska Institutet in Sweden has been published in the journal Diabetes.

It is well known that patients with type 2 diabetes have an increased risk of cardiovascular disease. Overtime type 2 diabetes may damage blood vessels, which could lead to life-threatening complications such as heart attack and stroke...

Increased consumption of whole grain foods could significantly reduce the incidence of type 2 diabetes and the costs associated with its treatment in Finland, according to a recent study by the University of Eastern Finland and the Finnish Institute for Health and Welfare. The findings were published in Nutrients.

“Our study shows that already one serving of full grains as part of the daily diet reduces the incidence of type 2 diabetes at the population level and, consequently, the direct diabetes-related costs, when compared to people who do not eat whole grain foods on a daily basis. Over the next ten years, society’s potential to achieve cost savings would be from 300 million (-3.3%) to almost one billion (-12...