ultrafast separation and purification of DNA fragments tagged posts

Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform. Microsystems & Nanoengineering, 2017; 3: 17001 DOI: 10.1038/micronano.2017.1

University of Twente researchers in The Netherlands developed a glass microchip for ultrafast separation and purification of DNA fragments. The chip, moreover, is easy to produce and cheap. The new chip is capable of fractionating DNA fragments within just a few minutes, while conventional approaches take hours. The chip does this in high resolution and also purifies the fragments; it removes the other salts in the DNA sample. Tiny amounts of DNA, like in medical diagnostics or in forensics, will be sufficient...