UVRAG tagged posts

Image: Most UVRAG complexes, multifunctional. UVRAG directly binds phosphorylated Bif, Beclin 1, Bax, CEP63 and DNA-PK, forming distinct protein complexes to regulate autophagosome formation, autophagosome maturation, endosome maturation, apoptosis, centrosome stability, DNA repair and genomic stability.

A new USC-led study identified a “sunscreen” gene that may help stave off skin cancer. The researchers found “UV radiation Resistance Associated Gene”, UVRAG, is a tumor suppressor for skin cancer, the most common form of cancer in the US. Melanoma is the deadliest skin cancer. In fact, melanoma rates have doubled over the last 3 decades...